The Nuclear weapons are perhaps the most powerful superweapons in the world rivaling the Ion Cannons of GDI.


In Cargo of Death 3 C-5 Galaxies were transporting nukes from one place to uncharted locations in order to attack in ways they can't be stopped but GDI managed to stop their transports from reaching their destinations.

In The Third Tiberium War a nuke hit the philadelphia killing most of the GDI Leaders.